W. L. Gore & Associates, Inc. Logo
2016-01-05 13:30
  • Final study results demonstrate for the first time efficacy of long-lasting absorbable biosynthetic mesh in challenging hernia repairs; has potential to end biologics era in hernia repair
FLAGSTAFF, ARIZ.--(Business Wire/Korea Newswire) January 5, 2016 -- W. L. Gore & Associates, Inc. (Gore) today announced final results of a long-term, prospective, multicenter study[1] evaluating the use of GORE® BIO-A® Tissue Reinforcement, a biosynthetic mesh, in complex ventral hernia (CVH) repair in patients with contaminated wounds. Results of the study led by lead investigator Michael Rosen, MD, Cleveland Clinic, was accepted for publication in the Annals of Surgery.

Patients and physicians interested in learning more about the study can view the paper here.

Patients scheduled to undergo CVH repair often have a poor quality of life preoperatively because of a gastrointestinal fistula, mesh infection, or non-healing abdominal wound. With more than 100 patients enrolled, these study results showed improved quality of life and intact hernia repairs in 83 percent of patients when using GORE BIO-A Tissue Reinforcement. Typically, in this type of patient population, the recurrence rate is as high as 30 percent[2] with a biologic mesh. The investigators reported that no biosynthetic required complete removal due to infection.

“I think this study represents an important step forward in defining the most appropriate way to reconstruct complex abdominal wall defects,” said Dr. Rosen. “Bio A [GORE BIO-A Tissue Reinforcement] performed very well in this challenging group of patients and will provide a cost-effective alternative for reconstructive surgeons.”

GORE BIO-A Tissue Reinforcement, as a biosynthetic mesh, also provides cost savings over a biologic mesh. Biologic mesh is often more expensive than biosynthetic mesh due to the complexity of harvesting tissue from cadavers or animal sources, as well as the subsequent processing and storage requirements to avoid the risks of viral contamination.

GORE BIO-A Tissue Reinforcement is a uniquely designed web of biocompatible synthetic polymers that is gradually absorbed by the body, while its 3D matrix of open, highly interconnected pores facilitates tissue generation and healing. As a biosynthetic tissue scaffold, it is not derived from human or animal tissue but engineered for uniformity, consistency, and versatility. Clinical evidence demonstrates that the scaffold is replaced with favorable type I collagen.

“This study demonstrates for the first time something we have believed all along: a biosynthetic mesh offers specific advantages when compared with a biologic mesh,” said Ron Anderson, General Surgical Products Business Unit Leader. “By being both more cost-effective for hospitals and payors while also improving quality of life for patients, GORE BIO-A Tissue Reinforcement is truly advancing healthcare and the way we treat CVH.”

Annals of Surgery, the world’s most highly referenced surgery journal, provides the international medical community with information on significant contributions to the advancement of surgical science and practice. Surgeons look to Annals of Surgery first for innovations in practice and technique.


At Gore Medical, we have provided creative therapeutic solutions to complex medical problems for 40 years. During that time, 40 million innovative Gore Medical Devices have been implanted, saving and improving the quality of lives worldwide. Our extensive family of products includes vascular grafts, endovascular and interventional devices, surgical meshes for hernia and soft tissue reconstruction, staple line reinforcement materials, and sutures for use in vascular, cardiac, and general surgery. We are one of a select few companies to appear on all of the U.S. “100 Best Companies to Work For” lists since the rankings debuted in 1984. For more information, visit www.goremedical.com.

[1] Rosen M, Bauer JJ, Harmaty M, et al. Multicenter, prospective, longitudinal study of the recurrence, surgical site infection, and quality of life after contaminated ventral hernia repair using biosynthetic absorbable mesh: the COBRA Study. Annals of Surgery. In press.

[2] Rosen M, Carbonell A, Cobb W, et al. Multicenter prospective longitudinal trial evaluating recurrence, surgical site infection and quality of life after contaminated ventral hernia repair using biosynthetic absorbable mesh. Presented at the 1st World Conference on Abdominal Wall Hernia Surgery; April 25-29, 2015; Milan, Italy. Hernia 2015;19(2)Supplement 2:S106. CO16:03.
GORE® and BIO-A® are trademarks of W. L. Gore & Associates.

View source version on businesswire.com: http://www.businesswire.com/news/home/20160104005412/en/
W. L. Gore & Associates, Inc. 전체 보도자료 보기
이 뉴스는 기업·기관이 발표한 보도자료 전문입니다. 언론 매체와 블로그는 보도를 목적으로 이 보도자료를 사용할 수 있습니다. 보도자료 등록 안내
Media Contact

Chempetitive Group for W. L. Gore & Associates
Andrea Vuturo
(858) 457-2436

이 보도자료 관련 분야

건강  의료기기  개발  해외

관심 분야 보도자료 구독 방법

가입하면 관심 분야 보도자료를 마이 뉴스와 이메일로 볼 수 있습니다. 스마트폰과 RSS로도 가능합니다.

보도자료 배포 서비스 안내

뉴스와이어는 4천여개 언론매체에서 일하는 1만7천여명의 기자에 보도자료를 배포해 언론이 보도할 수 있게 합니다.

해외 보도자료 배포 안내
비즈니스와이어와 제휴해 해외 언론에 보도자료를 배포합니다.